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Sho Yamasaki

Position Visiting Professor
Research Projects Project for Host Response
Division Division of Molecular Immunology
TEL +81 92 642 4614
FAX +81 92 642 4614
E-mail yamasaki[at]biken.osaka-u.ac.jp
プロフィール写真

Specialities

Immunology, Bacteriology

Main topics of research

Main publications

  1. Miyake Y, Toyonaga K, Mori D, Kakuta S, Hoshino Y, Oyamada A, Yamada H, Ono K, Suyama M, Iwakura Y, Yoshikai Y, Yamasaki S: C-type lectin MCL is an FcRγ-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor. Immunity 38:1050-62, 2013.
  2. Ishikawa T, Itoh F, Yoshida S, Saijo S, Matsuzawa T, Gonoi T, Saito T, Okawa Y, Shibata N, Miyamoto T, and Yamasaki S: Identification of distinct ligands for the C-type lectin receptors Mincle and Dectin-2 in the pathogenic fungus Malassezia. Cell Host Microbe 13:477-88. 2013
  3. Furukawa A, Kamishikiryo J, Mori D, Toyonaga K, Okabe Y, Toji A, Kanda R, Miyake Y, Ose T, Yamasaki S, and Maenaka K: Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL. Proc. Natl. Acad. Sci. USA. 110:17438-43. 2013
  4. Ishikawa E, Miyake Y, Hara H, Saito T, Yamasaki S: Germ-line elimination of electric charge on pre-T-cell receptor (TCR) impairs autonomous signaling for β-selection and TCR repertoire formation. Proc. Natl. Acad. Sci. USA. 107:19979-84, 2010.
  5. Ishikawa E, Ishikawa T, Morita YS, Toyonaga K, Yamada H, Takeuchi O, Kinoshita T, Akira S, Yoshikai Y, Yamasaki S: Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle. J. Exp. Med. 206:2879-88, 2009.
  6. Yamasaki, S., Ishikawa, E., Sakuma, M., Hara, H., Ogata, K. and Saito T: Mincle is an ITAM-coupled activating receptor that senses damaged cells. Nat. Immunol. 9: 1179-1188, 2008.
  7. Yamasaki, S. Ishikawa, E., Sakuma, M., Ogata, K., Sakata-Sogawa, K., Hiroshima, M., Wiest, D.L., Tokunaga, M. and Saito, T: Mechanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development. Nat. Immunol. 7: 67-75, 2006.