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小林和善

職種 特任助教
所属プロジェクト RNA制御プロジェクト
研究部門 真菌症研究部門
分野 RNA感染治療学分野
TEL 043-226-2801
FAX
E-mail k-kobayashi[at]chiba-u.jp
プロフィール写真

専門分野

分子生物学

研究テーマ

転写因子NF-kappaBの阻害法の開発

所属学協会

日本分子生物学会、日本癌学会

主な発表論文、著書

    Researchmap

    1. Kobayashi K*, Hiramatsu H*, Nakamura S, Kobayashi K, Haraguchi T, Iba H. (* equally contributed) Tumor suppression via inhibition of SWI/SNF complex-dependent NF-κB activation. Scientific Reports, 7:11772 (2017)
    2. Kobayashi K, Suemasa F, Sagara H, Nakamura S, Ino Y, Kobayashi K, Hiramatsu H, Haraguchi T, Kurokawa K, Todo T, Nakano A, Iba H. MiR-199a inhibits secondary envelopment of Herpes Simplex Virus-1through the downregulation of Cdc42-specific GTPase activating protein localized in Golgi apparatus. Scientific Reports, 7:6650 (2017)
    3. Hiramatsu H, Kobayashi K, Kobayashi K, Haraguchi T, Ino Y, Todo T, Iba H. The role of the SWI/SNF chromatin remodeling complex in maintaining the stemness of glioma initiating cells. Scientific Reports, 7:889 (2017)
    4. Haraguchi T, Kondo M, Uchikawa R, Kobayashi K, Hiramatsu H, Kobayashi K, Ung CW, Shimizu T, and Iba H. Dynamics and plasticity of the epithelial to mesenchymal transition induced by miR-200 family inhibition. Scientific Reports 6: 21117, 2016.
    5. Kobayashi K, Sakurai K, Hiramatsu H, Inada K, Shiogama K, Nakamura S, Suemasa F, Kobayashi K, Imoto S, Haraguchi T, Ito H, Ishizaka A, Tsutsumi Y, Iba H. The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines. Scientific Reports 5: 8428, 2015.
    6. Tagawa T, Haraguchi T, Hiramatsu H, Kobayashi K, Sakurai K, Inada K, and Iba H. Multiple microRNAs induced by Cdx1 suppress Cdx2 in human colorectal tumor cells. Biochem. J. 447:449-455, 2012.
    7. Ishizaka A, Mizutani T, Kobayashi K, Tando T, Sakurai K, Fujiwara T, and Iba H. Double PHD finger proteins DPF3a and 3b are required as transcriptional coactivators in the SWI/SNF complex-dependent activation of the NF-kB RelA/p50 heterodimer. J. Biol. Chem. 287:11924-11933, 2012.