研究
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巽浩一郎

職種 特任教授
所属プロジェクト 呼吸器生体制御解析プロジェクト
研究部門 呼吸器生体制御学寄附研究部門
分野
TEL 043-226-2577
FAX 043-226-2176
E-mail tatsumi[at]faculty.chiba-u.jp
プロフィール写真

専門分野

呼吸器内科学

研究テーマ

  1. 難治性呼吸器疾患に対する新規治療戦略の探索
  2. 呼吸器疾患合併による不眠症病態の解明と治療法の開発
  3. 生体制御の観点からの呼吸器感染症の病態解明

所属学協会

日本内科学会、日本呼吸器学会、日本循環器学会、日本肺高血圧・肺循環学会
American Thoracic Society（ATS）

主な発表論文、著書

2019年度

2020年度

2021年度

    Researchmap

    1. Arano T, Imamoto T, Suda R, Kasai H, Sugiura T, Shigeta A, Yamamoto K, Nagata J, Sakao S, Tanabe N, Tatsumi K. Heritable pulmonary arterial hypertension complicated by multiple pulmonary arteriovenous malformations. Respir Med Case Rep. 2021;32:101352. doi:10.1016/j.rmcr.2021.101352.
    2. Kasai H, Shikino K, Saito G, Tsukamoto T, Takahashi Y, Kuriyama A, Tanaka K, Onodera M, Yokoh H, Tatsumi K, Yoshino I, Ikusaka M, Sakao S, Ito S. Alternative approaches for clinical clerkship during the COVID-19 pandemic: online simulated clinical practice for inpatients and outpatients-A mixed method. BMC Med Educ. 2021;21:149. doi: 10.1186/s12909-021-02586-y.
    3. Kasuya Y, Kim JD, Hatano M, Tatsumi K, Matsuda S. Pathophysiological Roles of Stress-Activated Protein Kinases in Pulmonary Fibrosis. Int J Mol Sci. 2021;22:6041. doi: 10.3390/ijms22116041.
    4. Hirasawa Y, Nakada TA, Shimazui T, Abe M, Isaka Y, Sakayori M, Suzuki K, Yoshioka K, Kawasaki T, Terada J, Tsushima K, Tatsumi K. Prognostic value of lymphocyte counts in bronchoalveolar lavage fluid in patients with acute respiratory failure: a retrospective cohort study. J Intensive Care. 2021;9:21. doi: 10.1186/s40560-021-00536-w.
    5. Hiwasa T, Wang H, Goto KI, Mine S, Machida T, Kobayashi E, Yoshida Y, Adachi A, Matsutani T, Sata M, Yamagishi K, Iso H, Sawada N, Tsugane S, Kunimatsu M, Kamitsukasa I, Mori M, Sugimoto K, Uzawa A, Muto M, Kuwabara S, Kobayashi Y, Ohno M, Nishi E, Hattori A, Yamamoto M, Maezawa Y, Kobayashi K, Ishibashi R, Takemoto M, Yokote K, Takizawa H, Kishimoto T, Matsushita K, Kobayashi S, Nomura F, Arasawa T, Kagaya A, Maruyama T, Matsubara H, Tomiita M, Hamanaka S, Imai Y, Nakagawa T, Kato N, Terada J, Matsumura T, Katsumata Y, Naito A, Tanabe N, Sakao S, Tatsumi K, Ito M, Shiratori F, Sumazaki M, Yajima S, Shimada H, Shirouzu M, Yokoyama S, Kudo T, Doi H, Iwase K, Ashino H, Li SY, Kubota M, Tomiyoshi G, Shinmen N, Nakamura R, Kuroda H, Iwadate Y. Serum anti-DIDO1, anti-CPSF2, and anti-FOXJ2 antibodies as predictive risk markers for acute ischemic stroke. BMC Med. 2021;19:131. doi: 10.1186/s12916-021-02001-9.
    6. Matsumura A, Shigeta A, Kasai H, Yokota H, Terada J, Yamamoto K, Sugiura T, Matsumura T, Sakao S, Tanabe N, Tatsumi K. Interventricular septal curvature as an additional echocardiographic parameter for evaluating chronic thromboembolic pulmonary hypertension: A single-center retrospective study. BMC Pulm Med. 2021 in press. doi:10.21203/rs.3.rs-199528/v1.
    7. Mukae H, Kaneko T, Obase Y, Shinkai M, Katsunuma T, Takeyama K, Terada J, Niimi A, Matsuse H, Yatera K, Yamamoto Y, Azuma A, Arakawa H, Iwanaga T, Ogawa H, Kurahashi K, Gon Y, Sakamoto H, Shibata Y, Tamada T, Nishioka Y, Haranaga S, Fujieda S, Miyashita N, Mochizuki H, Yokoyama A, Yoshihara S, Tamaoki J; JRS guidelines committee for the management of cough and sputum. The Japanese respiratory society guidelines for the management of cough and sputum (digest edition). Respir Investig. 2021 May;59(3):270-290.
    8. Ogo T, Shimokawahara H, Kinoshita H, Sakao S, Abe K, Matoba S, Motoki H, Takama N, Ako J, Ikeda Y, Joho S, Maki H, Saeki T, Sugano T, Tsujino I, Yoshioka K, Shiota N, Tanaka S, Yamamoto C, Tanabe N, Tatsumi K. Selexipag for the treatment of chronic thromboembolic pulmonary hypertension. Eur Respir J. 2021 in press.
    9. Okunaga I, Shikano K, Kasai H, Koike K, Kawasaki T, Kuriyama A, Iawasawa S, Sugiura S, Tanzawa H, Tatsumi K. A case of intractable medication-associated osteonecrosis of the jaw complicated by cervical abscess and sepsis. Chiba Medical J. 2021;97E:49-56. doi:10.20776/S03035476-97E-4-P49.
    10. Shigeta A, Tanabe N, Naito A, Yokota H, Kato F, Sanada TJ, Sakao S, Ishida K, Masuda M, Tatsumi K. Preoperative soluble cluster of differentiation 40 ligand level is associated withoutcome of pulmonary endarterectomy. JTCVS Open. 2021 in press.
    11. Shikano K, Abe M, Shiko Y, Tsushima K, Yoshioka K, Ishiwata T, Kawasaki T, Ikari J, Terada J, Kawasaki Y, Tatsumi K. What are the factors affecting the recovery rate of bronchoalveolar lavage fluid? Clin Respir J. 2021 Nov 10. doi: 10.1111/crj.13462. Online ahead of print.
    12. Shimada A, Kawata N, Sato H, Ikari J, Suzuki E, Anazawa R, Suzuki M, Masuda Y, Haneishi H, Tatsumi K. Dynamic quantitative magnetic resonance imaging assessment of areas of the lung during free-breathing of patients with chronic obstructive pulmonary disease. Acad Radiol. 2021;S1076-6332(21)00205-1. Online ahead of print. doi: 10.1016/j.acra.2021.03.034.
    13. Shimomura I, Watanabe N, Yamamoto T, Kumazaki M, Tada Y, Tatsumi K, Ochiya T, Yamamoto Y. Selective targeting of KRAS-driven lung tumorigenesis via unresolved ER stress. JCI Insight. 2021;6:e137876. doi: 10.1172/jci.insight.137876.
    14. Shinkai M, Tsushima K, Tanaka S, Hagiwara E, Tarumoto N, Kawada I, Hirai Y, Fujiwara S, Komase Y, Saraya T, Koh H, Kagiyama N, Shimada M, Kanou D, Antoku S, Uchida Y, Tokue Y, Takamori M, Gon Y, Ie K, Yamazaki Y, Harada K, Miyao N, Naka T, Iwata M, Nakagawa A, Hiyama K, Ogawa Y, Shinoda M, Ota S, Hirouchi T, Terada J, Kawano S, Ogura T, Sakurai T, Matsumoto Y, Kunishima H, Kobayashi O, Iwata S. Efficacy and Safety of Favipiravir in Moderate COVID-19 Pneumonia Patients without Oxygen Therapy: A Randomized, Phase III Clinical Trial. Infect Dis Ther. 2021 Dec;10(4):2489-2509.
    15. Suzuki J, Kasai H, Terada J, Shikano K, Sasaki A, Suzuki H, Nakajima T, Kouchi Y, Shiina M, Kobayashi T, Ohwada C, Ikeda JI, Yoshino I, Tatsumi K. Bronchiolitis obliterans after stem cell transplantation for hematologic malignancies rescued by lung transplantation: A report of two cases. Respir Investig. 2021:S2212-5345(21)00050-2. Online ahead of print. doi:10.1016/j.resinv.2021.03.007.
    16. Suzuki Ｙ, Sekine A, Nishiyama A, Sugiura T, Tanabe N, Isaka Y, Hashimoto Y, Okaya T, Kuriyama A, Nagata J, Shigeta A, Sakao S, Tatsumi K, Suzuki T. A case of pulmonary arterial hypertension with V/Q SPECT/CT that showed localized uptake of 99mTc just below the pleura and a unique distribution. Respirol Case Rep. 2021;9:e0847. doi: 10.1002/rcr2.847.
    17. Takahashi Y, Yamamoto K, Sakao S, Takeuchi T, Suda R, Tanabe N, Tatsumi K. The clinical characteristics, treatment, and survival of portopulmonary hypertension in Japan. BMC Pulm Med. 2021;21:89. doi: 10.1186/s12890-021-01452-3.
    18. Takeshita Y, Terada J, Fujita R, Hirasawa Y, Kinoshita T, Isaka Y, Kinouchi T, Tajima H,Tada Y, Kiryu S, Tsushima K. Coronary artery calcium score may be a novel predictor of COVID-19 prognosis: a retrospective study. BMJ Open Respir Res. 2021 Jul;8(1):e000923.
    19. Takeshita Y, Terada J, Hirasawa Y, Kinoshita T, Tajima H, Koshikawa K, Kinouchi T, Isaka Y, Shionoya Y, Tada Y, Tsushima K. High-flow nasal cannula oxygen therapy in hypoxic patients with COVID-19 pneumonia: A retrospective cohort study confirming the utility of respiratory rate index. Respir Investig. 2021 Oct 30:S2212-5345(21)00185-4.
    20. Tamura Y, Kumamaru H, Abe K, Satoh T, Miyata H, Ogawa A, Tanabe N, Hatano M, Yao A, Tsujino I, Fukuda K, Kimura H, Kuwana M, Matsubara H, Tatsumi K. Improvements in french risk stratification score were correlated with reductions in mean pulmonary artery pressure in pulmonary arterial hypertension: A subanalysis of the Japan Pulmonary Hypertension Registry (JAPHR). BMC Pulm Med. 2021;21:28. doi: 10.1186/s12890-021-01398-6.
    21. Tanabe N, Kumamaru H, Tamura Y, Taniguchi H, Emoto N, Yamada Y, Nishiyama O, Tsujino I, Kuraishi H, Nishimura Y, Kimura H, Inoue Y, Morio Y, Nakatsumi Y, Satoh T, Hanaoka M, Kusaka K, Sumitani M, Handa T, Sakao S, Kimura T, Kondoh Y, Nakayama K, Tanaka K, Ohira H, Nishimura M, Miyata H, Tatsumi K. Multi-institutional prospective cohort study of patients with pulmonary hypertension associated with respiratory diseases. Circ J. 2021;85:333-342. doi:10.1253/circj.CJ-20-0939.
    22. Tomii K, Terada J, Chin K. Increased usage of the high flow nasal cannula in COVID-19 cases in Japan -from the online questionnaire survey by the Japanese Respiratory Society. Respir Investig. 2021 Sep;59(5):666-669.
    23. Yamamoto K, Tanabe N, Takahashi Y, Naito A, Sekine A, Suda R, Jujo Sanada T, Sugiura T, Shigeta A, Sakao S, Tatsumi K. Characteristics of patients meeting the new definition of pre-capillary pulmonary hypertension (Nice 2018) in a single Japanese pulmonary hypertension center. BMC Pulm Med. 2021;21:260. doi: 10.1186/s12890-021-01623-2.